Federer, who was bidding to extend his record eight men's titles, was ousted Wednesday by free-hitting Kevin Anderson, who battled back from a two-sets-to-none deficit.
In fact, Anderson had actually been improving with every game after looking clearly shell-shocked in the first set, illustrated by the relief on his face when Federer narrowly missed a net approach in the fifth game.
Once the fifth set went beyond 10 games, Federer's level began to dip.
Anderson was the runner-up to Nadal at last year's U.S. Open, but he never made it beyond the fourth round at Wimbledon until this week. Inevitably, the match went the whole length and then some more, until Anderson grabbed the only break-point in the entire set.
"I just kept on telling myself, 'I have to keep believing.' I kept saying that today was going to be my day", Anderson said, "because you really need that mindset taking the court against somebody like Roger".
After a slump following two years of nearly total domination of the men's game, Djokovic's star appears to be back on the rise and he is a clear contender to win a fourth Wimbledon title. "I hopefully have two more matches to play in the tournament".
Kevin Anderson did the unthinkable on Wednesday, rallying from two sets down against the always great Roger Federer in a grueling Wimbledon quarterfinal match to advance to his first semifinal. Depends against who you play you have less or more chances to win.
The two-time Wimbledon champion will face Djokovic, a three-time victor at the All England Club, who leads their epic head-to-head rivalry 2625.
Elsewhere in the men's bracket, Novak Djokovic has had a lot of ups and downs over the past few years, but he's back in the semifinal of a Grand Slam.
It is the second time that 20-times Grand Slam champion Federer has lost at Wimbledon from two sets ahead, suffering the same fate against Jo-Wilfried Tsonga in the 2011 quarter-finals. Can Nadal's body stand up to another tough test less than 48 hours after playing for 12 minutes short of five hours with Del Potro?
Earlier on Centre Court, Djokovic overcame Nishikori and his own bad behavior (twice smacked with code violations for racket abuse and a time violation) to become the first to earn a spot in Friday's semifinals with a 6-3, 3-6, 6-2, 6-2 victory. After that, I never really felt exactly 100%.
Anderson had 28 aces in the victory, compared to Federer's 16 aces.
Up a set and serving for the second, Federer got angry at a call that was reversed by the Hawk-Eye system.
"Facing off that match point, then getting a break the next minute, I'm like, "I've got the third set in the bag". Two hours later, Federer had squandered a two-set lead, shocked in a Wimbledon quarterfinals marathon by No. 8 seed Kevin Anderson. I had my chances and blew them, so.
Anderson continued to grow in confidence and stature as the match wore on, holding his nerve to earn his first win over Federer in five attempts.
'He's kept himself healthy, he's kept himself efficient - he is remarkable and it amazes me probably more than most people because I remember being 36, retiring and it was abrupt, ' Agassi said.
The RAF was formed with the amalgamation of the Royal Flying Corps (RFC) and the Royal Naval Air Service (RNAS) on 1st April 1918. Prince Louis will wear the handmade replica of the Royal Christening Robe, made by The Queen's dressmaker, Angela Kelly.
Croatia lost that encounter 2-1 before going on to secure bronze - until Wednesday their best performance at a global finals. We've watched every game, rated every player and constructed a top 10 or 20 for each spot and crowned the kings of each.
The regulatory boost comes less than 24 hours after Comcast upped its offer for Sky, hours after 21st Century boosted its own bid. Fox originally bid £10.75 in December 2016, but its bid was trumped in February by Comcast, which bid £12.50.
The US has told India and other countries to cut oil imports from the Gulf nation to "zero" by November 4 or face sanctions. USA officials said in June they would push countries to reduce their Iranian oil imports to zero.
There is speculation that North Korea may also want payment for the return of the remains, our correspondent adds. But it didn't commence at the scheduled time as North Korean officials didn't show up.
For their part, Napoli have already replaced Sarri with former Blues manager Carlo Ancelotti , who started the new role on July 1. That takes the total amount the compensation the London club has paid out in recent times up to a remarkable £89.3M.
Modric says his side will spend the days leading up to the semi-final clash. working on how to nullify England's threat. It followed another humiliating defeat the previous year - Croatia lost 4-1 to England at home.
That's how they know about his "VIP" remark and it's how they know that the claim he can't prepare for the trial is nonsense. Truesdale Adult Detention Center - Thursday morning, according to a spokesperson for the Alexandria Sheriff's Office.
The Senator from Iowa chairs the Senate Judiciary Committee, which he said will take a few days or weeks to review Kavanaugh . Although Republicans have a 51-49 advantage in the Senate, the absence of Sen. "That's what it comes down too", said Jipping.