The news is likely to impact the share price of WPP as well as have wider implications for the advertising industry, including WPP AUNZ.
"It is hard to see a future for WPP", the chief executive said.
WPP's corporate development director and chief operating officer for Europe Andrew Scott and, Wunderman CEO Mark Read would don the mantle of co-chief operating officers.
WPP said Sorrell would be treated as having retired, with chairman Roberto Quarta becoming executive chairman until a new chief executive is appointed.
Sorrell, 73, will step aside immediately, according to a statement late on Saturday by WPP.
Earlier this month, the board of WPP appointed an independent counsel to investigate Sorrell for personal misconduct. His departure followed allegations of personal misconduct and misuse of company assets and comes days before the board was set to publish the findings of their investigation. "However, I believe it is in the best interests of the business if I step down now", said Sorrell.
Having denied the unspecified allegation made against him by a whistleblower, Sir Martin's decision to resign will inevitably spark speculation about the nature of the claims made against him.
Mr Sorrell is among the most influential advertising professionals globally and also the longest-serving FTSE-100 chief executive, who has run WPP since setting up the business in 1985. Sir Martin would of course assist with the transition. WPP's shares have lost a third of their value of the past year-far more than rivals facing the same market challenges-as its financial guidance has repeatedly proved too optimistic.
Some multinational advertisers, including P&G, which owns Ariel and Gillette, have signalled their intention to take more of their marketing services activity in-house, reducing the lucrative work for which they are charged by external agencies.
He added in a letter sent to WPP staff: "As I look ahead, I see that the current disruption is simply putting too much unnecessary pressure on the business, our 200,000 people and their 500,000 or so dependents, and clients we serve in 112 countries".
WPP has seen its shares fall by almost a third during the last 12 months, although it still has a market capitalisation of more than £15bn.
"Once WPP breaks up, the pressure on the other guys will be irresistible", he added.
But it doesn't depend on the United result, it's in our hands, it's up to us to win our games, and we are able to win two games'. City let slip a 2-0 lead to lose 3-2 in the Manchester derby on 7 April, when victory would have clinched the title.
Maple Leaf Sports and Entertainment has closed Jurassic Park because of wintry weather that has descended on Toronto. The Raptors opened as 8.5-point favorites; the total is at 210.5, according to sportsbooks monitored by OddsShark.
From there, the Bruins content to ride the coattails of one magical player and coast to a 7-3 win in Game 2 of the first round. Gallant: It just turned it into the somber mood like, now we got to go into that dressing room and talk to them.
The Correct Score market affords us an opportunity to combine what we believe the match result and the number of goals will be. Puel has been handed a boost, with the news that Burnley captain, Ben Mee will miss this clash with a knee injury.
Cuomo campaign spokeswoman Abbey Fashouer on Saturday said Cuomo's "record of progressive accomplishment is unmatched". The Working Families Party said it was pleased to show independence from Cuomo, the Democratic Party's flagbearer.
Since Oakwood doesn't have a home pool, Rickard and Tompkins usually practice at the Morgan Hill Aquatic Center. Oakwood's swim team members also excel academically and are well-rounded in the endeavors they pursue.
Mr Buckel was the lead attorney in a case involving Brandon Teena , a transgender man murdered in the U.S. state of Nebraska. Early Saturday morning , people at Prospect Park noticed Buckel's body before first responders arrived on the scene.
Hynes wasn't ready to discuss whether he'll change starting goaltenders for the next game. "It's going to be very tough for us". The Devils have played well in spurts, overcoming slow starts to keep both games interesting. "The guys care a lot, " he said.
The interview, conducted by George Stephanopoulos, took place in Comey's home in Virginia last Monday, according to Axios . Trump slammed Comey on Friday morning and called him a "proven LEAKER & LIAR" and a "weak and untruthful slime ball".
A 2010 egg-related salmonella outbreak led to more than 550 million getting pulled from shelves and thousands became sick. The eggs from the Hyde County farm reached consumers in 10 states, including New Jersey, New York and Pennsylvania.