The blast took place at about 11am on Sunday, just outside the Varby Gard underground station in Huddinge, a residential district in greater Stockholm, said regional police spokesman Sven-Erik Olsson.
Officers say a 60-year-old man was hurt after picking up an object from the ground which exploded. "But we will have to wait for the technical investigation", the spokesman said, adding that a murder investigation had been launched.
It is being reported by local media that the second injured person is a 45-year-old woman.
The man was taken the hospital but his injuries proved fatal.
"Someone has used some type of explosive material", Lars-Ake Stevelind, a rescue official, told Swedish television station SVT.
But police haven't confirmed the exact nature of the explosive device.
Police cordoned off the station and the square where the blast happened as the bomb squad moved in to investigate.
"I heard a huge bang", one local resident told Swedish paper Aftonbladet.
Numerous illegal hand grenades found in Sweden are being imported from former Yugoslav nations, he said.
Van Dyke's wife, Shirley Ann Jones, told the newspapers his health had deteriorated since a vehicle accident two years ago. In his final TV role in 2015, Jerry Van Dyke reprised his role on " The Middle ", guesting alongside his brother, Dick.
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Variety reports that the show, starring Brandon Micheal Hall as a hip-hop artist who is elected mayor, is "effectively canceled". The network's half-hour bench includes its Roseanne revival, family comedy Splitting Up and Zach Braff vehicle Alex, Inc .
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