Multiple dead, multiple injured after incident in downtown Manhattan

US President Donald Trump and Sayfullo Saipov

O'Neill said the suspect "did make a statement" after the crash, which led police to declare the incident an act of terrorism. The vehicle struck multiple people on the path. The two-lane path is separated by a low median from West Street, part of the West Side Highway.

Police in New York City are responding to a report of gunfire a few blocks from the World Trade Center memorial in Manhattan. Two others died at the hospital and 11 people have serious but non-life threatening injuries, police say. He then continued south and hit a school bus, according to the NYPD.

The department writes on Twitter that Saipov got out of a rented Home Depot van displaying imitation firearms and was shot by police officers. Multiple law enforcement officials tell ABC News that the suspect in custody has been identified as 29-year-old Sayfullo Saipov from Tampa, Florida.

City Hall said Mayor Bill de Blasio had been briefed about the incident.

In video from the scene, several bodies and bicycles were strewn along a bike path alongside Chambers and West streets. New York Gov. Andrew Cuomo was also headed to the scene.

New York Police Department says that one person is in custody, and that an investigation into the incident is ongoing.

Tom Gay, a school photographer, was on Warren Street and heard people saying there was an accident.

President Trump and the first lady both tweeted responses.

"Our thoughts and prayers are with all those affected", White House Press Secretary Sarah Huckabee Sanders said.

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