Charlie Nicholas' predictions for this week's Champions League matches

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Tottenham manager Mauricio Pochettino has refused to give a concrete answer over the availability of talisman Harry Kane for the clash against Real Madrid.

Both Tottenham and Madrid sit on level in Group H with seven points apiece, with a win for either side all-but confirming their entry into the Round of 16.

Two of Europe's most prolific goalscorers will again go head-to-head at Wembley on Wednesday but, with Kane expected to be recovered from the hamstring injury that forced him out of the defeat against Manchester United on Saturday, Vertonghen paid his team-mate a glowing compliment.

"With the doctors and the player, we will take the best decision for everyone", said Pochettino. We feel very confident going into the game, in a good, or not good form, and I think that Real are quality.

Harry Kane has returned to training with the squad, but there are still doubts whether he will start against Real Madrid at Wembley.

"It may be possible but I don't want to say 100 per cent as we have one more day".

Varane picked up an adductor muscle issue in Sunday's shock 2-1 La Liga defeat at Girona, with Isco also suffering a thigh problem late in the game.

The Spurs centre-back has lauded the in-form hitman on the eve of the Lilywhites' Champions League clash with Los Blancos at Wembley. We're going to go into the game expecting of ourselves that we can do it and we're looking forward to it.

"We're in good shape". Sometimes, it is better to play them after a loss and sometimes they can be relaxed and confidenct. It's not just me saying that, the results speak for themselves.

Real trail eight points behind leaders Barcelona after losing two and drawing two of their opening 10 games and Zidane has faced pointed questions about his tactics and motivational abilities for the first time. We don't know and we'll have to see.

Asked if they could win without him, he said: "Yeah, definitely".

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