It continues a disappointing year for 29-year-old Kerber, who has not won a title since her victory in NY 12 months ago.
But perhaps it wasn't so surprising after Kerber played so poorly after her breakthrough 2016, when she also won the Australian Open and lost to Serena Williams in the Wimbledon final. "I knew that everything was going the right way, but I was a little bit injured and it's still not 100 percent with my elbow", the sixth seed said.
"But the end of the first set was very important. It's nostalgic every time I come here, so I'm always really happy to play here".
Osaka also converted four break points and won 63.2 percent of Kerber's second serves-again, a sign of her dominance. Last year, Osaka lost to American Madison Keys in the third round.
That next match will be against either a qualifier or Denisa Allertova, who is ranked more than 40 places below her at 90.
"The site", Osaka said, "feels really familiar to me".
Kerber, who despite her poor form held the number one spot until Wimbledon, will now fall outside the top 10.
Moments later, her eyes darting around the room, she added, "This year is a completely different year". It was later announced all matches outside of Arthur Ashe Stadium were canceled for the day.
She almost upended Keys in the U.S. Open's third round past year, leading 5-1 in the third set before losing in a tiebreaker, a collapse on her mind in the latter stages Tuesday.
In total, only nine singles matches were due to be completed out of a scheduled 64.
Nadal, this year's French Open champion, is 12-0 in first round meetings in New York; Federer is 16-0.
Heis bidding for a record sixth crown in NY.
And arguably, it all started here for the 25-year-old in a final finish that took in wins over both Williams sisters.
Two-time Grand Slam champion Kerber struggled badly with her second serve, winning only 37% of points behind it.
Pliskova, who is seeded No. 1, easily advanced by beating Magda Linette 6-2, 6-1, French Open champion Jelena Ostapenko got past Lara Arruabarrena 6-2, 1-6, 6-1 in a match that started on Court 17 then was moved indoors at Ashe, and No. 23 Barbora Strycova defeated Misaki Doi 6-1, 6-3.
Also in action are 2004 champion Kuznetsova, who meets Marketa Vondrousova of the Czech Republic, and French Open victor Jelena Ostapenko, up against Lara Arruabarrena of Spain.
Khosrowshahi has served as a member of Expedia's board since it was spun off from IAC/InterActiveCorp. two years ago. Uber's dysfunctional culture includes rampant sexual harassment and allegations of deceit and corporate espionage.
As for Beyonce, who is from Houston originally, she posted a message to Instagram , writing: "Texas, you are in my prayers". As we all know, Hurricane Harvey has devastated parts of Texas and Louisiana.
Lee has been accused of offering bribes of 38 million United States dollars for various departments after the death of his father. The party chief expressed the hope that the case may act as an opportunity for Samsung to become a socially responsible company.
This year's Call of Duty will include a dedicated multiplayer social space for the first time, known as Headquarters . Experience classic Call of Duty combat, the bonds of camaraderie, and the unforgiving nature of war .
Llamas said, "It stands to reason we will see some other kinds of applications that are possibly not health and fitness oriented". Beyond all that, there doesn't seem to be much particular advantage in picking Fitbit's headphones over the competition.
Both lawsuits argue the ban violates the Fifth Amendment, which guarantees equal protection and substantive due process. Trump had announced the ban in a series of tweets on July 26, reversing a policy of his predecessor, Barack Obama.
The acquisition follows the launch of CBS All Access , the company's digital subscription VOD service in the Australian market. CBS Corporation is listed on the New York Stock Exchange, and has a current market capitalisation of ~US$28 billion.