Former minister Anna Soubry called on Mrs May to sack her joint chiefs of staff, Fiona Hill and Nick Timothy, after she complained about their central roles in the campaign.
Beleaguered British Prime Minister Theresa May is appointing new members of her government after several of them lost their seats in Parliament in this week's general election that proved disastrous for her Conservative Party.
May's attempts to form a government with Northern Ireland's Democratic Unionist Party (DUP) appear to be taking longer than first thought, as Downing Street said Saturday negotiations are ongoing despite an earlier statement that a deal had been reached.
In a statement on the website Conservative Home, Timothy said he took "full responsibility" for his role in the defeat, but blasted "bizarre media reports" about his role in the election campaign.
He said he regretted not including a pledge to cap social care costs in the party's widely criticised manifesto.
Ms Hill said last night that it had been "a pleasure to work with such an excellent Prime Minister", adding: 'I have no doubt at all that Theresa May will continue to serve and work hard as Prime Minister - and do it brilliantly'.
They were her most trusted advisors.
Amid reports that senior Tories were sounding out potential replacements for Mrs May, prominent Conservative MP Heidi Allen said the Prime Minister had six months at most left in Downing Street.
Earlier, May's director of communications until the election was announced, Katie Perrior, called the campaign "pretty dysfunctional", telling the BBC she "needed to broaden her circle of advisers and have a few grey hairs in there who been around a bit and could say "don't do that". But I would like to make clear that the freakish media reports about my own role in the policy's inclusion are wrong: "it had been the subject of many months of work within Whitehall, and it was not my personal pet project", Timothy wrote on the Conservative Home website.
The strong showing for Labour in the election was capped when the party snatched the final seat to declare, Kensington, by just 20 votes late on Friday.
In his resignation letter, Timothy said that the campaign had failed to convey May's "positive plan for the future" to voters and urged Conservatives to rally behind the embattled prime minister.
"But I would like to make clear that the weird media reports about my own role in the policy's inclusion are wrong: it had been the subject of many months of work within Whitehall, and it was not my personal pet project", he said. "Well, the mandate she's got is lost Conservative seats, lost votes, lost support and lost confidence".
The leader of the Scottish Conservatives, Ruth Davidson, tweeted a link to a speech she had made about same-sex marriage - something the DUP opposes.
"One of them is country, one of the others is LGBTI rights".
'They only really know one way to operate - and that is to have enemies and I'm sure I'm one of them this morning'. A petition on Change.org had more than half a million signatures by Saturday afternoon, calling for May's resignation over her alliance with the DUP.
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